You can read the Plain Language Summary here.
Developing a Core Outcome Set for Hospital Deprescribing Trials
Huge thanks to all involved from the following hospital sites
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University Hospitals of Coventry and Warwickshire NHS Trust
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Northumbria Healthcare NHSFT
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Salford Royal NHSFT
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Wrightington, Wigan and Leigh Teaching Hospitals NHSFT
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Royal Devon & Exeter Hospital NHSFT
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Cambridge University Hospital
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Newcastle upon Tyne Hospitals NHSFT
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University Hospital Southampton NHSFT
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The Queen Elizabeth Hospital Kings Lynn NHSFT
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Norfolk & Norwich University Hospitals NHSFT
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Royal Cornwall Hospitals NHS Trust
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Liverpool University Hospitals NHSFT
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Hull University Teaching Hospitals NHS Trust
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Fairfield General Hospital, Pennine Acute NHS Hospitals NHS Trust, part of Northern Care Alliance
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Harrogate & District NHSFT
OVERVIEW
In order to determine whether our CHARMER intervention is effective, we have developed a set of core outcomes (effects). This will determine what outcomes are the most important for us to measure, to test whether the CHARMER intervention is safe and effective. The process we used to ask our stakeholders about the important outcomes was called a ‘Delphi study’.
We asked participants in this study to look at a list of outcomes collated from previous research studies and the expertise of the CHARMER research team. This list was refined by participants to ensure the selected outcomes were the most pertinent effects to measure.
The finalised selection of outcomes has become part of the core outcome set. We will collect data on these outcomes in Work Package 3 (feasibility study) and Work Package 4 (definitive trial) to test the CHARMER intervention. The core outcome set will also provide an agreed standardised set of outcomes that should be measured and reported in all subsequent hospital deprescribing trials.
PUBLIC AND PATIENT INVOLVEMENT
Patient and public involvement members advised on the design and content of materials for practitioner participants and worked collaboratively with work package leads to develop the patient/carer study materials. They also supported preparation with research assistants to undertake telephone interviews with stakeholders and were integral members of the research team when analysing results from the Delphi study.
WORK PACKAGE LEADS
RESEARCH FELLOW
If you have any questions about Work Package 1, please contact Dr Jackie Martin.